LABCRUX GUIDE

Mean, standard deviation, and SEM

Mean, sample SD, and SEM summarize different properties and must be labeled explicitly in text, tables, and error bars.

Mean describes center

The arithmetic mean is the sum divided by the observation count. It can be sensitive to outliers and may not represent a skewed distribution well.

Sample SD describes spread

Sample standard deviation commonly uses n − 1 when estimating population variability from a sample.

SEM describes estimated mean precision

SEM equals sample SD divided by the square root of n. It decreases with larger sample size and is not the spread of individual observations.

Label every summary

State n and identify whether error bars show SD, SEM, confidence intervals, or something else. Consistent symbols without definitions remain ambiguous.

Sources and boundaries

  1. [1]

    NIST/SEMATECH e-Handbook of Statistical Methods

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